Are there any side-effects from long-term use of a topical antibiotic for acne vulgaris?

351 viewsDermatologjiaAcne vulgaris
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Are there any side-effects from long-term use (2–3 months) of a topical antibiotic for acne vulgaris?

Local irritation occurs but generally topical antibiotics are safe.
Propionibacterium acnes-resistant strains occur.

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