Sanofi, GSK reach virus vaccine deals with US, EU


loading...
A lab technician in Personal Protective Equipment (PPE) looks at a reagent bottle before performing vaccine tests at French phar
A lab technician in Personal Protective Equipment (PPE) looks at a reagent bottle before performing vaccine tests at French pharmaceutical giant Sanofi’s lab in Val de Reuil

Pharma giants Sanofi and GSK will receive up to $2.1 billion from the US government for the development of a COVID-19 vaccine, the companies said Friday, as the world scrambles for an answer to the pandemic.

At the same time, the European Union said it had reached a deal with Sanofi for the supply of 300 million doses of a potential vaccine.

The European Commission, the bloc’s executive arm which negotiated the agreement, said it would allow all 27 EU member countries to purchase the vaccine once it was proven to be safe and effective.

The United States has identified a under development by Sanofi and GSK for its “Operation Warp Speed,” which aims to rapidly secure millions of doses.

The firms aim to combine a Sanofi-developed antigen, which stimulates the production of germ-killing antibodies, with GSK’s adjuvant technology, a substance that bolsters the immune response triggered by a vaccine.

The American money will “help fund the development activities and secure scale-up of Sanofi’s and GSK’s manufacturing capabilities in the United States… resulting in a significant increase in capacity.”

“The US government will provide up to $2.1 billion, more than half of which is to support further development of the vaccine, including clinical trials, with the remainder used for manufacturing scale-up and delivery of an initial 100 million doses,” the companies said.

“The US government has a further option for the supply of an additional 500 million doses longer term,” they added.

The United States is the country the worst hit by the coronavirus outbreak, with over 150,000 deaths out of the global toll of more than 667,000.

Europe meanwhile has recorded nearly 210,000 deaths from 3.2 million cases, and with infections rising again in several countries there are fears a “second wave” of the pandemic could be on the way.

Sanofi, based in France, and GSK of Britain said of their vaccine should start in September, with a Phase 3 study under way by the end of the year.

Billion doses per year

“If the data are positive, the companies can request US regulatory approval in the first half of 2021. In parallel, Sanofi and GSK are scaling up manufacturing of the antigen and adjuvant to produce up to one billion doses per year globally,” they said.

US Health and Human Services Secretary Alex Azar said the portfolio of vaccines being assembled under Operation Warp Speed “increases the odds that we will have at least one safe, effective vaccine as soon as the end of this year.”

The United States has already committed some $6 billion since March to vaccine projects with pharma giants such as Johnson & Johnson, Pfizer and AstraZeneca.

The latest investment holds the “potential to bring hundreds of millions of safe and effective doses to the American people,” Azar said in the statement.

The companies said discussions were also under way with the European Commission and other governments “to ensure global access to a novel coronavirus vaccine.”

The partners intended to supply “a significant portion of total worldwide available supply capacity” in 2021 and 2022 to an initiative seeking to ensure equitable global access to COVID-19 tests, treatments and vaccines.

‘Global public good’

Sanofi CEO Paul Hudson drew the ire of French officials in May when he suggested any COVID-19 vaccine would be offered first to the US government because it had been investing in its development.

Under pressure, he later indicated it would be available to everyone at the same time.

Other countries too, have been investing in a vaccine against the novel coronavirus, with Sanofi and GSK announcing a deal with Britain on Wednesday for 60 million doses.

Laboratories need the money to accelerate the early stages of vaccine development and prepare production units without fearing they will be left out of pocket if the candidate drugs fail.

In turn, governments seek to ensure they will get the first doses if the vaccines do work.

Such deals have drawn criticism for leaving behind poor countries who do not have the cash to conclude such contracts.

Earlier this month, the UN Human Rights Council stressed the importance of “equitable and unhindered access” to diagnostics, treatments and vaccines, and said any developed against COVID-19 should be considered a “global public good”.


Follow the latest news on the coronavirus (COVID-19) outbreak


© 2020 AFP

Citation:
Sanofi, GSK reach virus vaccine deals with US, EU (2020, July 31)
retrieved 31 July 2020
from https://medicalxpress.com/news/2020-07-sanofi-gsk-virus-vaccine-eu.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.



Related posts:

Poor hygiene is significant risk for antimicrobial-resistant bacteria colonization
Exploring connections between ovarian cancer and blood cells
Review suggests postmenopausal women at risk for nonalcoholic fatty liver disease
Is the COVID-19 virus pathogenic because it depletes specific host microRNAs?
Study hints, can't prove, survivor plasma fights COVID-19
Bayern Munich batters Barcelona 8-2 to reach Champions League semi-finals
Older Children and the Coronavirus: A New Wrinkle in the Debate
UK secures 90 mn more doses of potential virus vaccine
Gum Disease Tied to Colon Cancer Risk
Cardiovascular risk factors tied to COVID-19 complications and death
Obesity Raises the Risk of Death From Covid-19 Among Men
Targeting the LANDO pathway holds a potential clue to treating Alzheimer's disease
Managing Pandemic Health Risks on College Campuses
Researchers overturn hypothesis underlying the sensitivity of the mammalian auditory system
EU ministers agree to new round of sanctions on Belarus
Coronavirus: When Will Long-Term Care Facilities Reopen to Visitors?
US, Canada, Mexico COVID-19 travel ban extended
BMJ-Studie: Vorhofflimmern weniger tödlich als früher, aber dennoch Anlass zur Sorge
Where the Democrats’ Kamala Harris stands on the issues
Clinical Trials of Coronavirus Drugs Are Taking Longer Than Expected
Germany puts most of Spain on Covid-19 quarantine list
Google adding new coronavirus-related details to travel search results
Stress und Wut können Herzinsuffizienz verschlimmern
One I.C.U., Five Patients: A Different View of the Virus’s Toll
Patients' access to opioid treatment cumbersome
Aktualisiertes Faltblatt informiert über das Hodgkin Lymphom
European nations step up virus measures as cases mount
France pays tribute to aid workers killed in Niger
Uniklinikum Würzburg: Medikamenten-Duo gegen Lymphknotenkrebs sehr erfolgreich
Counties with higher proportion of Black residents have more COVID-19 cases, deaths
Klimawandel als Herausforderung für Nieren und Spermien
UK adds France, Netherlands to travel quarantine list
French forensic teams, FBI join probe into cause of explosion
66 Millionen Euro für das Berliner Spin-Off T-knife
Stay or go? Brits in France face virus dilemma over two-week quarantine
Iran, Turkey slam Israel-UAE deal, others welcome 'historic step'
CDK12-Expression steht in Zusammenhang mit biochemischem Rezidiv und Immunstatus bei Prostatakrebs
Paris, Marseille named high-risk Covid-19 zones, making restrictions more likely
Mexico to keep US border closed to non-essential travel
Amid the devastation, old tensions surface
Überlastung der Sehnen im Sport - Was ist zu tun?
COVID-19 vaccine will be free for Americans: officials
Human chain protects Hindu temple amid riots over Facebook post
Corona-Stiftung fördert zwei junge Schlaganfallforscher
Texas hospitalizations below 7,000 for first time in weeks
Versorgungsdaten für die medizinische Forschung
Racial and ethnic disparities in flu vaccination rates among US dialysis facilities
„World Restart a Heart Day“ am 16. Oktober
Uncertainty surrounds Israel’s West Bank plans after UAE deal
You can start drug addiction treatment over the phone—and thanks to COVID, more people are starting ...
Rolle der Thrombozyten bei Alzheimer weiter aufgeklärt
Israeli air strikes target Hamas positions in Gaza over incendiary balloons
Inspired by essential workers, teenage brothers use a 3-D printer to make face shields
Trump blocks postal funds in attempt to stop Americans from voting by mail
Pandemic hampers reopening of joint replacement gold mine
CDC tells parents, docs to watch for rare, neurologic condition in children this fall
Taliban inmates set to be freed pose danger 'to the world', says Afghan president
Why is stroke a bigger threat to black people?
France to reciprocate Britain's Covid-19 quarantine, says minister
Anxiety and Depression Rises Among Young Adults, Blacks and Latinos in Pandemic
Smoking strongly linked to women's lower take up of cancer screening services
Surge in Spain's Covid-19 cases prompts regional smoking ban
Feel Like You’re Going Out of Your Mind? Consider Your Mind-Set
Neuroscientist discusses how coronavirus pandemic stress alters brain chemistry
You Probably Won’t Catch the Coronavirus From Frozen Food
Heavy class A drug use linked to heightened risk of sight loss in US military
Protestors form 'solidarity chains' to condemn post-vote crackdown in Belarus
Leipzig beat Atletico to reach Champions League last four, face PSG for final spot
Coronavirus Live Updates: 5 South Texas Communities Become Leading U.S. Hot Spots
Levels of anxiety, addiction, suicidal thoughts are soaring in the pandemic
MBZ, the UAE strongman behind historic deal with Israel
Don’t Like What You See on Zoom? Get a Face-Lift and Join the Crowd.
Loss of a specific enzyme increases fat metabolism and exercise endurance in mice
France Covid-19 cases 'growing fastest among young' amid second wave fears
Medical marijuana associated with fewer hospitalizations for individuals with sickle cell disease
What was more deadly for New Yorkers—COVID-19 or the 1918 flu?
SARS-CoV-2 und Verlust des Geruchssinns – Möglicher Mechanismus
Maternal weight tied to early-onset neonatal bacterial sepsis
Bakterien: Wer schneller wächst, ist früher tot
Living Near an Airport May Raise Risks of Preterm Birth
UK begins testing a new app to fight COVID-19 spread
COVID-19: Immunsystem auf Irrwegen - Biermann Medizin
Israel, UAE normalise relations in historic, Trump-brokered deal
In N.Y.C.’s Coronavirus Surge, a Frightening Echo of the 1918 Flu
Iraq reports 24-hour virus toll record of over 3,800
Blasenkrebs: Reduzierte BCG-Dosis führt zu mehr Rezidiven
Lebanon's military gets sweeping new powers amid anger over Beirut explosion
Whether You Are a Night Owl or Early Bird May Affect How Much You Move
Mask exemptions for people with disabilities have not been made clear – and this threatens human rig...
Analyse: Raumluftreiniger reduzieren Infektionsgefahr - Biermann Medizin
Coronavirus Live Updates: New Zealand Races to Trace Source of New Outbreak
Digital technologies and data privacy in the COVID-19 pandemic
Verfolgung neuer Vogelgrippeviren durch Analysen der Genomdaten möglich
Israel targets Hamas in Gaza in response to fire-bomb balloons
Baby George born amid Beirut blast wreckage
On Native American Land, Contact Tracing Is Saving Lives
Virus uses decoy strategy to evade immune system, research reveals
Forscher weisen intaktes Coronavirus in Aerosolen nach
Did extremists in Pakistan really uproot “un-Islamic” trees?
New Jersey Gym Owners Are Desperate to Reopen
loading...

Leave a Reply

Your email address will not be published. Required fields are marked *