DR ELLIE CANNON: What is blue toe syndrome and how can Dad control it?


My father, who’s 82, has been diagnosed with blue toe syndrome, which I am told is caused by poor circulation. How can he keep it under control? Blue toe syndrome, also known as trash foot, is caused by a blockage in the small blood vessels of the foot.  This reduces the blood flow to the […]

Coronavirus: Scientist claims preservative in AstraZeneca vaccine could explain blood clot link


A preservative in AstraZeneca‘s Covid vaccine may trigger a rare overreaction from the immune system that causes blood clots, a scientist has claimed. Tiny numbers of people given the jab or the one made by Johnson & Johnson have developed a clotting condition that spooked some countries into turning their backs on it. The reasons for this […]

Coronavirus: Covid can cause erectile dysfunction months later, study claims


Coronavirus can cause erectile dysfunction months after a man has recovered from the illness, according to a study.   Miami University scientists scanned the penis tissue of two recovered Covid patients aged 65 and 71 who were struggling to get erections. And, in what they claimed was a world-first, they found the virus was still lingering […]

Researchers provide reassuring findings to the majority who have had COVID-19 — ScienceDaily


Mild Covid-19 infection is very unlikely to cause lasting damage to the structure or function of the heart, according to a study led by UCL (University College London) researchers and funded by the British Heart Foundation (BHF) and Barts Charity. The researchers say the results, published in JACC Cardiovascular Imaging, should reassure the public, as […]

‘I went through the menopause at 13’: Woman tells her moving story in a new TV show


For a teenager, it was an unexpected and shocking diagnosis: blood tests and an ultrasound confirmed that, at 13, Hayley Cockman had gone into premature menopause. Her periods had stopped within a year of starting, and then symptoms such as night sweats, hot flushes and poor concentration kicked in. ‘At school, I’d be sitting in […]

Engineering diseased human skin in vitro — ScienceDaily


The skin, which covers the surface of the human body, is its largest organ. It is the first organ to show changes stemming from organ or physiological activity. It is especially common for diabetic patients to suffer from skin diseases or infections. Recently, a POSTECH research team has succeeded in creating a 3D artificial skin […]

Beaming infrared light into the ear could combat hearing loss, tests show 


Shooting infrared light into the ear may prevent one of the most common causes of hearing loss — and even restore hearing that’s been damaged. That’s the thinking behind a new U.S. trial. Previous research suggests that infrared light can prevent the death of hair cells, which are key to hearing, as well as trigger […]

Short-term spikes in air pollution ‘may speed up brain decline in older men’


CAUSE CHILDREN TO HAVE A LOW IQ: Researchers at the University of California, San Francisco, found in May 2019 that children born to mothers who live in polluted areas have an IQ that is up to seven points lower than those living in places with cleaner air. CAUSE CHILDREN TO HAVE POORER MEMORY: Researchers at the […]

Why does air come out my ear when I blow my nose? DR MARTIN SCURR answers your health questions


Air escapes from my ear when I blow my nose. I can even blow bubbles out of it when I’m underwater. It’s not painful but surely it can’t be right? I’m 67. Carol Lawrence, Morecambe, Lancashire. Air coming out of the ear is a classic sign of a perforated eardrum. The eardrum (or tympanic membrane) […]

PROFESSOR ROY TAYLOR explains the science behind type 2 diabetes


Barely a day goes by without type 2 diabetes hitting the headlines. Last week alone there were two major stories about the condition.  A study from French researchers showed that if you develop type 2 in middle age, it doubles your risk of getting dementia by the age of 70. Another study, which looked at […]

One cup of leafy greens a day lowers risk of heart disease, study says


Eating just one cup of raw vegetables daily, such as leafy greens like spinach, boosts your cardiovascular health, a new study reveals. In a sample of over 50,000 people, the biggest eaters of nitrate-rich vegetables had lower blood pressure and up to 26 per cent lower risk of heart disease, experts found.  Just one cup is […]

Pre-diabetes nearly DOUBLES the risk of having a heart attack or stroke, study finds


Pre-diabetes nearly DOUBLES the risk of having a heart attack or stroke because high blood sugar damages the arteries, study finds Pre-diabetes is when sugar levels are high but not as high as type 2 diabetes It is common and thought to affect a third of adults in the US and 7million Brits   And now […]

Novel non-coding RNAs regulating blood vessel formation — ScienceDaily


Researchers at the University of Eastern Finland have discovered previously unknown non-coding RNAs (ncRNAs) involved in regulating the gene expression of vascular endothelial growth factors (VEGF), the master regulators of angiogenesis. The study, conducted by the research groups of Associate Professor Minna Kaikkonen-Määttä and Academy Professor Seppo Ylä-Herttuala, provides a better understanding of the complex […]

Healthy young adults who had COVID-19 may have long-term impact on blood vessels and heart health — ScienceDaily


New research published in Experimental Physiology highlights the possible long term health impacts of COVID-19 on young, relatively healthy adults who were not hospitalized and who only had minor symptoms due to the virus. Increased stiffness of arteries in particular was found in young adults, which may impact heart health, and can also be important […]

DR MICHAEL MOSLEY: How fasting could help cut your blood pressure


Regular readers of this column might wonder if I am ever so slightly obsessed with the microbiome, the billions of tiny creatures that live in our guts — and you’d be right. I’m fascinated by these extraordinary microbes, and the ongoing battle between the ‘good’ and the bad’ ones, that influences so much about us, […]

HEALTH NOTES: People with kidney disease are 70% more likely to develop dementia, study finds


HEALTH NOTES: People with kidney disease are 70 per cent more likely to develop dementia, study finds By Mail on Sunday Reporter Published: 17:12 EDT, 8 May 2021 | Updated: 17:26 EDT, 8 May 2021 People with kidney disease are 70 per cent more likely to develop dementia, a major study has found. Swedish researchers […]

Researchers use ultrasound to develop delivery system for potent RNA drugs — ScienceDaily


RNA-based drugs have the potential to change the standard of care for many diseases, making personalized medicine a reality. This rapidly expanding class of therapeutics are cost-effective, fairly easy to manufacture, and able to go where no drug has gone before, reaching previously undruggable pathways. Mostly. So far, these promising drugs haven’t been very useful […]

Cancer-linked mutation accelerates growth of abnormal stroke-causing brain blood vessels — ScienceDaily


Researchers have discovered an explanation for why cerebral cavernous malformations (CCMs) — clusters of dilated blood vessels in the brain — can suddenly grow to cause seizures or stroke. Specifically, they found that a specific, acquired mutation in a cancer-causing gene (PIK3CA) could exacerbate existing CCMs in the brain. Furthermore, repurposing an already existing anticancer […]

Should you ignore the food traffic lights?


You see them on food packets — red, amber and green colours that are supposed to depict whether the food you are putting in your basket is healthy — or not. Introduced in 2013 by the Food Standards Agency, the traffic light colours are assigned for levels of fat, saturated fat, sugar and salt. The […]

In mice, therapy based on natural molecules improves lung function — ScienceDaily


A new treatment is among the first known to reduce the severity of acute respiratory distress syndrome caused by the flu in animals, according to a new study. Tests in mice infected with high doses of influenza showed that the treatment could improve lung function in very sick mice and prevent progression of disease in […]

Smokers attending A&E will be handed vaping ‘starter packs’ in Government-funded trial


Smokers attending A&E will be handed vaping ‘starter packs’ in Government-funded trial to see if it helps them kick the habit Initiative at five NHS hospitals will see smokers at A&E units offered e-cigarettes  Research shows e-cigarettes can be a useful tool to help people quit tobacco  Devices are controversial as people can become addicting […]

Having type 2 diabetes in middle age could double dementia risk, study finds


People who develop type 2 diabetes before they turn 60 could double their risk of developing dementia in old age, a study has claimed. French scientists found that dementia at age 70 was twice as likely if someone had been diagnosed with diabetes 10 years earlier. The risk was also increased for people who got […]

Stress slows the immune response in sick mice — ScienceDaily


The neurotransmitter noradrenaline, which plays a key role in the fight-or-flight stress response, impairs immune responses by inhibiting the movements of various white blood cells in different tissues, researchers report April 28th in the journal Immunity. The fast and transient effect occurred in mice with infections and cancer, but for now, it’s unclear whether the […]

Preclinical discovery triggers wound healing, skin regeneration — ScienceDaily


Difficult-to-treat, chronic wounds in preclinical models healed with normal scar-free skin after treatment with an acellular product discovered at Mayo Clinic. Derived from platelets, the purified exosomal product, known as PEP, was used to deliver healing messages into cells of preclinical animal models of ischemic wounds. The Mayo Clinic research team documented restoration of skin […]

‘Jelly’ that could renew damaged knee joints


An injection of jelly could help treat worn-out joints. Scientists hope the jab, using jelly found in donated umbilical cords, will stimulate the growth of cushioning cartilage once injected into the knees of patients with osteoarthritis. Tests on animals suggest the jelly — called Wharton’s jelly — can potentially reverse damage to joints caused by […]

HEALTH NOTES: Surfing the web comes of age in lockdown


HEALTH NOTES: Surfing the web comes of age in lockdown as study finds it boosts mental health of older people By Mail on Sunday Reporter Published: 17:01 EDT, 24 April 2021 | Updated: 17:01 EDT, 24 April 2021 Surfing the web boosted the mental health of older people during lockdown. A University of Surrey study found […]

Newly-discovered molecule provides dual protection against vascular inflammation — ScienceDaily


A multidisciplinary team of researchers from Duke-NUS Medical School and the Agency for Science, Technology and Research (A*STAR) in Singapore discovered a new mitochondrial peptide called MOCCI that plays an important role in regulating inflammation of blood vessel and immunity. The study, published in the journal Nature Communications, revealed how one gene encoded two molecules […]

Force transmission between cells orchestrates collective cellular motion — ScienceDaily


How do the billions of cells communicate in order to perform tasks? The cells exert force on their environment through movement — and in doing so, they communicate. They work as a group in order to infiltrate their environment, perform wound healing and the like. They sense the stiffness or softness of their surroundings and […]

Having a sweet tooth could lead to heart disease and death in middle age, study finds


Having a sweet tooth could lead to heart disease and an early death, a study has suggested. University of Oxford scientists tracked 116,000 people’s eating habits for up to 15 years and checked whether they had been admitted to hospital or died.  They found people who regularly indulged in chocolate bars and sugary drinks were more […]

Disrupted sleep is linked to increased risk of early death, particularly in women — ScienceDaily


For the first time, a study has shown a clear link between the frequency and duration of unconscious wakefulness during night-time sleep and an increased risk of dying from diseases of the heart and blood vessels, and death from any cause, particularly in women. The study of 8001 men and women, which is published today […]

Findings cast doubt on industry promotion of these products as ‘safer’ alternative — ScienceDaily


The impact on lung cells of Heat not Burn products — a hybrid between traditional cigarettes and electronic vaping devices — may be no less harmful than that of conventional cigarettes, suggest the findings of a small comparative study, published online in the journal Thorax. Heat not burn products contain nicotine and tobacco, but have […]

Targeted chemotherapy of glioblastoma spheroids with an iontronic pump — ScienceDaily


Despite surgery and subsequent treatment with chemotherapy and radiation, the majority of patients experience recurrence of malignant brain tumours. Researchers at Linköping University, Sweden, and the Medical University of Graz, Austria, have shown in cells in culture that an ion pump can deliver drugs more accurately, which gives less severe adverse effects in chemotherapy. The […]

New type of cell contributes to increased understanding of ALS — ScienceDaily


The causes of the serious muscle disease ALS still remain unknown. Now, researchers at Karolinska Institutet and KTH Royal Institute of Technology, among others, have examined a type of cell in the brain blood vessels that could explain the unpredictable disease origins and dynamics. The results indicate a hitherto unknown connection between the nervous and […]

Coronavirus does not infect the brain but still inflicts damage, study finds — ScienceDaily


SARS-CoV-2, the virus that causes COVID-19, likely does not directly infect the brain but can still inflict significant neurological damage, according to a new study from neuropathologists, neurologists, and neuroradiologists at Columbia University Vagelos College of Physicians and Surgeons. “There’s been considerable debate about whether this virus infects the brain, but we were unable to […]

Mother who was given five per cent chance of survival loses four limbs


A brave mother who had four limbs amputated and was given a five per cent chance of surviving after contracting sepsis admits she ‘wished she was dead’ due to the illness. Allison Friday, 56, from Hartlepool, County Durham, was put into a coma in February last year and her family was told to prepare for the […]

DR ELLIE CANNON: Why won’t anyone fix these upsetting marks on my face?


I have suffered from acne since the age of 12 – I am now 78. As I’ve got older, I’ve also developed skin tags on my eyelids, and brown marks.  My GP tried to refer me to a dermatologist, but they wouldn’t see me as my problems are cosmetic. I get really upset at the state […]

Study strengthens links between red meat and heart disease — ScienceDaily


An observational study in nearly 20,000 individuals has found that greater intake of red and processed meat is associated with worse heart function. The research is presented at ESC Preventive Cardiology 2021, an online scientific congress of the European Society of Cardiology (ESC). “Previous studies have shown links between greater red meat consumption and increased […]

Approximately one-fourth of ARDS patients have disease features that put them at increased risk of death within the first month of hospitalization — ScienceDaily


Approximately one in four patients hospitalized for the acute respiratory distress syndrome (ARDS) associated with severe COVID-19 infections may have a distinct phenotype (disease presentation) or biochemical profile associated with organ dysfunction, blood-clotting abnormalities and greater risk of death than patients with other, seemingly similar forms of the disease, researchers at Massachusetts General Hospital (MGH) […]

New study links red meat consumption with heart disease


UK scientists have linked the consumption of any form of red meat – such as beef, lamb and pork – with a decline in heart function.  The researchers, who studied nearly 20,000 individuals, found that greater intake of red and processed meat was linked with a decline in three different measures of heart health.   Processed […]

HALF of children who develop inflammatory syndrome linked to COVID-19 have neurologic symptoms


HALF of children who develop inflammatory syndrome linked to COVID-19 have neurologic symptoms including hallucinations and brain damage Researchers looked at 46 pediatric patients diagnosed with multisystem inflammatory syndrome in children (MIS-C) MIS-C is a condition in which different body parts become inflamed and is linked to children infected with COVID-19 Of the 46 children […]

How to tackle heel pain and get back on your feet: DR MARTIN SCURR addresses your health issues 


My wife is a keen walker, but has not been able to walk for months due to heel pain. Her doctor and podiatrist both suggested plantar fasciitis, but it does not hurt in the typical area, and she has not responded to treatment. She is 67. Peter Goode, via email. Heel pain, as your wife […]

Another way ‘good’ cholesterol is good: Combatting inflammation — ScienceDaily


Testing how well “good” cholesterol particles reduce inflammation may help predict who is at heightened risk to develop cardiovascular disease caused by narrowed arteries, according to research published today in the American Heart Association’s flagship journal Circulation. Assessing levels of high-density lipoprotein (HDL) cholesterol, known as “good cholesterol,” are already a standard part of formulas […]

Tube that props open blood vessels could conquer impotence


A tube that props open tiny blood vessels may offer a new way to tackle impotence.  The wire tube, or stent, is implanted inside the tiny arteries measuring just 1mm wide that supply blood to the penis. The stent is designed to widen arteries that have become furred up as a result of atherosclerosis, where […]

Experts’ medicine cabinet essentials: The shopping list to keep your family healthy


The past year has taught us the importance of a stocked medicine cabinet.  Whatever health problem you face —from cuts and stings to a thumping headache or even mild symptoms of Covid, such as fever — it is vital to have the correct, up-to-date products to hand.  And it’s equally important to have them organised […]

Experts are worried that using the Body Mass Index is not a fat lot of good 


During a year of grim statistics, it was one of the grimmest. Launching its £10 million anti-obesity strategy last summer, Public Health England (PHE) warned that being severely obese could increase the chance of death in those who caught Covid-19 by up to 90 per cent. Shedding excess pounds, PHE advised, was one of most […]

Early cannabis use linked to heart disease — ScienceDaily


Smoking cannabis when you’re young may increase your risk of developing heart disease later, according to a recent University of Guelph study. In the first study to look at specific risk indicators for cardiovascular disease (CVD) in young, healthy cannabis users, researchers found subtle but potentially important changes in heart and artery function. Cigarette smoking […]

Why do I cough all the time as if I have to clear my throat? DR ELLIE CANNON answers your questions 


I constantly feel as if I have phlegm stuck in my throat. I’m always coughing to try to clear it, and I also suffer terrible breath. What is wrong with me, and is there anything I can do? Feeling as though there’s phlegm always in the throat (something stuck in your throat is a different […]

Saved… the jaws that are wrecked by radiotherapy


People with debilitating jaw fractures caused by cancer treatment could be spared risky surgery by a breakthrough drug combo that heals damaged bone. Radiotherapy to the head and neck, given for tongue, throat and nose cancers, can lead to problems with blood vessels connected to the lower jaw. This can trigger infections in the bone […]

Brisk walking 5 times a week may combat brain aging, study suggests


A brisk walk around the block several times a week could do wonders to preserve a healthier mind – as well as body – as you age, a new study suggests.    In a year-long study conducted by University of Texas, Southwestern, researchers found that middle aged and older Americans scored higher on cognitive tests and […]

How to defuse the male fertility timebomb


Could a toxic soup of chemicals in everyday life be destroying men’s ability to father children?  That is the latest claim from a U.S. expert, Dr Shanna Swan, who made headlines in 2017 with research that suggested human sperm counts are plummeting. Dr Swan, a professor of environmental medicine and public health at the Icahn […]

New tablet promises to prevent AND treat crippling migraines


One of those involved in the rimegepant trials, Darlene LeBlanc, 63, describes how the drug was the first treatment she’d tried in over 40 years that worked well for her debilitating symptoms For almost three decades, Jennifer Farrington’s life had been dominated by migraines so bad that the GP had to go on sick leave […]

Health remedies by Royal appointment: Harry’s ring to improve sleep and Kate’s bug-resistant gloves


Both the Duchess of Cambridge and the Queen wear gloves from Cornelia James, some of which are made from fabric treated with an anti-microbial coating called HeiQ Viroblock Cornelia James Imogen Gloves are seen above We all have our favourite products we rely on for our health needs — and the Royal Family is no […]

HEALTH NOTES: Gene tests identify risks associated with ‘silent’ strokes 


HEALTH NOTES: Gene tests identify risks associated with ‘silent’ strokes By Mail on Sunday Reporter Published: 17:01 EDT, 3 April 2021 | Updated: 17:19 EDT, 3 April 2021 Gene tests could one day be used to spot patients at risk of ‘silent’ strokes that cause dementia, scientists believe. Researchers studied genetic samples of thousands of people […]

Toward a reliable oral treatment for sickle cell disease — ScienceDaily


For the millions of people worldwide who have sickle cell disease, there are only a few treatment options, which include risky bone marrow transplants, gene therapy or other treatments that address a subset of symptoms. Today, researchers will describe the discovery of a small molecule with the potential to address the root cause of sickle […]

Will the Covid vaccine protect people who had to shield?


Actress Sheila Hancock, 88, recently revealed that she has been warned that the treatment she receives for rheumatoid arthritis (RA) may affect the efficacy of her Covid-19 vaccine More than half of the UK adult population has received the first dose of the Covid vaccine and, for the vast majority, that spells a passport to freedom […]

FDA approves new device to help protect athletes from traumatic brain injury


The C-shaped device, called the Q-Collar, fits around the back and side of the neck. It works by clamping down on blood vessels in the neck, which increases blood volume in the skull. This limits the movement of the brain inside the skull, which researchers believe generally causes traumatic brain injury.  The FDA said it […]

Comminuted open fractures and Tiger Woods’ other injuries, explained


The 45-year-old golf legend was rushed to Harbor-UCLA Medical Center on Tuesday after the wreck. The hospital’s chief medical officer described his injuries and immediate treatment in a statement posted to Woods’ Twitter account: “Mr. Woods suffered significant orthopaedic injuries to his lower right extremity that were treated during emergency surgery,” Dr. Anish Mahajan said. […]

Fauci says timeline for mass vaccinations could shift “maybe into mid-to-late May and early June”


A new study suggests that Covid-19 may cause damage to the eyes in critically ill patients.   For the study, published in the journal Radiology, researchers reviewed magnetic resonance imaging of 129 patients presenting with severe Covid-19 in France between March 4 and May 1.  Advanced imaging tests showed nine of the 129 (7%) patients had one […]

Here’s an idea to float—a space-ready sleeping bag to keep blood moving


A sleeping bag attached to a vacuum cleaner might not sound like the stuff giant leaps are made of. But researchers using just that have taken at least a small step toward solving a serious problem for space travelers. The problem is the way blood behaves in the absence of gravity. When you’re standing up […]

Could we use statins to treat COVID-19?


Statins lower cholesterol if taken daily – but may also have other effects on the body. Credit: StockLite/Shutterstock Nothing in medicine is as exciting as discovering new drugs. However, this process is time consuming, expensive and not always necessary. Sometimes, existing drugs can be used to manage illnesses that are different to those they were […]

Y-90 therapy offers many benefits in treatment of liver cancer


Credit: CC0 Public Domain My father has had chronic liver disease. Recently, he was diagnosed with liver cancer. His doctor mentioned Y-90 as one treatment option. What is Y-90, and is it safe? Chronic liver disease is the most common risk factor for the development of liver cancer, and patients frequently face both conditions at […]

Study finds 10 metabolites associated with risk of stroke


Credit: CC0 Public Domain Metabolites are small molecules found in our body’s cells. They come from the food we eat, chemical processes happening within our bodies and microbes. A new analysis of recent studies has found that the levels of 10 metabolites detected in the blood are associated with a person’s risk of stroke. The […]

Gene therapy gives man with sickle cell disease the chance for a better future


Evie Junior. Credit: UCLA Broad Stem Cell Research Center For Evie Junior, living with sickle cell disease has been like running a marathon. “But it’s a marathon where as you keep going, the trail gets rockier and then you lose your shoes,” the 27-year-old said. “It gets harder as you get older. Things start to […]

Protein regulating inflammation in atherosclerosis identified


Atherosclerosis is a condition affecting the cardiovascular system. If atherosclerosis occurs in the coronary arteries (which supply the heart) the result may be angina pectoris, or in worse cases a heart attack. Credit: Wikipedia/CC BY 3.0 The protein CARD8 regulates several inflammatory proteins in people with atherosclerosis. This is shown in a new study by […]

‘Turncoat’ macrophages in the tumor ‘micro-environment’ underlie breast cancer progression


Credit: CC0 Public Domain New research that is examining the “tumor microenvironment” reveals not only how macrophages can become extraordinary turncoats but also how they can actively support tumor growth and metastatic progression in certain forms of breast cancer. The tumor microenvironment—or TME—refers to the region encompassing a tumor, an area entangled with blood vessels […]

Dr. Mary Fowkes, 66, Dies; Helped Science Understand the Pandemic


Dr. Mary Fowkes, a neuropathologist at Mount Sinai Hospital in Manhattan whose autopsies of Covid-19 victims early in the pandemic discovered serious damage in multiple organs — a finding that led to the successful use of higher doses of blood thinners to treat patients — died on Nov. 15 at her home in Katonah, N.Y., […]

Quick bursts of exercise can help diabetics’ hearts


(HealthDay)—Frequent, short exercise sessions may be better for diabetes patients’ blood vessels than longer and fewer workouts, and that may reduce their risk of heart disease, according to a new study. People with type 2 diabetes are at increased risk for heart disease and reduced vascular (blood vessel) function, the study authors noted. Measuring vascular […]

Their Teeth Fell Out. Was It Another Covid-19 Consequence?


While Ms. Khemili had become more diligent about her dental care, she had a history of dental issues before contracting the coronavirus. When she went to the dentist the day after her tooth came out, he found that her gums were not infected but she had significant bone loss from smoking. He referred Ms. Khemili […]

Protein commonly screened for in pregnancy is linked to gestational diabetes


Stained tissue showing changes in blood vessels in fat tissue between nonpregnant and pregnant women. Credit: R. Rojas-Rodriguez et al., Science Translational Medicine (2020) Laboratory research and analysis of epidemiological data by Silvia Corvera, MD, and Tiffany Moore Simas, MD, MPH, MEd, and colleagues show that low levels of a protein commonly seen in screening […]

Eye exam could lead to early Parkinson’s disease diagnosis


An example of a fundus eye images taken from the UK Biobank. Credit: Radiological Society of North America A simple eye exam combined with powerful artificial intelligence (AI) machine learning technology could provide early detection of Parkinson’s disease, according to research being presented at the annual meeting of the Radiological Society of North America (RSNA). […]

Maraxilibat reduces debilitating itching in children with Alagille syndrome


Credit: CC0 Public Domain On behalf of Childhood Liver Disease Research Network (ChiLDReN), Texas Children’s Hospital and Baylor College of Medicine researchers report that prolonged treatment with Maraxilibat resulted in clinically meaningful improvements in debilitating itching (pruritus) and related quality of life outcomes in children with Alagille syndrome. This syndrome is a rare genetic systemic […]

Diabetes, hypertension may increase risk of COVID-19 brain complications


Chest X-ray of a SARS-CoV-2-positive patient exhibiting confusion and showing weakness on his left side shows pneumonia in the lower lungs. Credit: Radiological Society of North America Some patients with COVID-19 are at higher risk of neurological complications like bleeding in the brain and stroke, according to a study being presented at the annual meeting […]

Here’s three ways physical activity changes its very structure


Regular exercise changes the structure of our bodies’ tissues in obvious ways, such as reducing the size of fat stores and increasing muscle mass. Less visible, but perhaps even more important, is the profound influence exercise has on the structure of our brains – an influence that can protect and preserve brain health and function […]

New screening questionnaire can identify people at high risk of developing heart disease


More than 40% of middle-aged adults have silent coronary artery disease. Researchers have developed a new screening questionnaire to help identify individuals at the highest risk for coronary artery disease, according to late-breaking research presented today at the American Heart Association’s Scientific Sessions 2020. Coronary artery disease is caused by atherosclerosis, or deposits of fats, […]

Study shows mindfulness might not work as you expect


Credit: Unsplash/CC0 Public Domain If dispositional mindfulness can teach us anything about how we react to stress, it might be an unexpected lesson on its ineffectiveness at managing stress as it’s happening, according to new research from the University at Buffalo. When the goal is “not to sweat the small stuff,” mindfulness appears to offer […]

Diabetes epidemic detected among Xavante indigenous community in Central Brazil


Researchers examine retinas and find high prevalence of type 2 diabetes as well as ocular problems caused by the disease. Credit: Fernando Korn Malerbi The Xavante, one of the indigenous communities most vulnerable to SARS-CoV-2 in Brazil, are suffering from an epidemic of diabetes, a “silent” disease considered a risk factor for severe COVID-19. A […]

Down syndrome-associated gene suppresses age-related corneal clouding


Credit: CC0 Public Domain An analysis of aging in Down syndrome and hypercholesterolemia mouse models has suggested that a Down syndrome-associated gene, DSCR-1, protects against abnormal vascularization of the cornea and associated corneal opacity (blindness) by suppressing oxidized LDL cholesterol production and new downstream angiogenic signaling in patients with chronic high cholesterol. Epidemiological data suggests […]

Asian ethnicity strongly linked to COVID-related stroke


Credit: Unsplash/CC0 Public Domain Asian ethnicity is strongly linked to COVID-related stroke, reveals an analysis of stroke centre activity in England and Scotland during the first wave of the coronavirus pandemic, and accepted for publication in the Journal of Neurology Neurosurgery & Psychiatry. Among patients with ischaemic stroke, which is caused by a blocked artery, […]

The connection between diabetes, kidney disease and high blood pressure


It’s a triple health threat faced by tens of millions of Americans. But few think about it until they’re forced to. Even then, the interplay between diabetes, high blood pressure and kidney disease can be a challenge for people to grasp. But doctors say having an understanding is key for anybody who wants to reduce […]

Study shows myocarditis linked to COVID-19 not as common as believed


Credit: CC0 Public Domain A study conducted by Richard Vander Heide, MD, Ph.D., Professor and Director of Pathology Research at LSU Health New Orleans School of Medicine, and Marc Halushka, MD, Ph.D., Professor of Pathology at Johns Hopkins University School of Medicine, suggests myocarditis caused by COVID-19 may be a relatively rare occurrence. Their findings […]

Living in Noisy Neighborhoods May Raise Your Dementia Risk


Long-term exposure to noise may be linked to an increased risk for Alzheimer’s disease and other forms of dementia. Researchers did periodic interviews with 5,227 people 65 and older participating in a study on aging. They assessed them with standard tests of orientation, memory and language, and tracked average daytime noise levels in their neighborhoods […]

New strategy for treating common retinal diseases shows promise


In a new study, scientists test a possible new therapy for eye diseases that’s based on fragments of the CITED2 protein. Here, the protein interacts with tips of blood vessels in the retina. Credit: Ayumi Usui-Ouchi, Friedlander laboratory at Scripps Research Scientists at Scripps Research have uncovered a potential new strategy for treating eye diseases […]

Novel bioresorbable, tissue-healing surgical device approved by FDA


Recently approved by the U.S. Food and Drug Administration, this surgical screw secretes citrate to help damaged tissue heal. Credit: Acuitive Technologies A new surgical tendon fixation system that not only re-attaches damaged tissues but also facilitates healing as it is absorbed by the body has been granted 510(k) clearance by the U.S. Food and […]

When the Doctor Is a Covid ‘Long Hauler’


I am a physician who contracted what was initially a fairly mild case of Covid-19 in early March. Seven months later, I remain substantially debilitated, with profound exhaustion and a heart rate that goes into the stratosphere with even the tiniest bits of exertion, such as pouring a bowl of cereal or making a bed. […]

Some Signs of Recovery From Severe Covid


Even some patients originally deemed as candidates for a lung transplant managed to recuperate and go home without needing one, said Dr. Tiago Noguchi Machuca, a lung transplant surgeon at the University of Florida. He had treated patients on ventilators and ECMO machines — devices that infuse oxygen into the blood stream and remove carbon […]

Study reveals kidney disease or injury is associated with much higher risk of mortality for COVID-19 patients in ICU


Credit: Pixabay/CC0 Public Domain New research published in Anaesthesia (a journal of the Association of Anaesthetists) reveals the much higher risk of mortality faced by COVID-19 patients in intensive care who have chronic kidney disease (CKD) or, those who develop new (acute) kidney injury (AKI) as a result of developing COVID-19. CKD is a type […]

Research could change how blood pressure is managed in spinal cord injury patients


Credit: CC0 Public Domain New research from the International Collaboration on Repair Discoveries (ICORD) challenges the current standard for managing blood pressure in people with spinal cord injury (SCI). The findings, published today in Nature Communications, could lead to a change in the way newly injured patients have their blood pressure managed, potentially improving their […]

Flu and COVID-19 are bad enough, but they also can raise stroke risk


Adrienne Bresnahan/Moment, Getty Images It’s flu season. In the middle of a coronavirus pandemic. Is this any time to be thinking about your risk of stroke? Yes, researchers say. Having either influenza or the coronavirus seems to increase the odds of having an ischemic stroke—the type where blood flow in the brain is blocked. While […]

When Symptoms of Covid-19 Don’t Go Away


The range of reported symptoms is vast. They include unusual fatigue from physical or mental activity, brain fog, temperature irregularities, rashes, memory problems and insomnia. It’s as if the body’s immune response to the coronavirus has thrown the nervous system out of whack, according to Dr. Dayna McCarthy, rehabilitation specialist at the Mount Sinai Center […]

Improvements in stroke treatment could save more lives


Credit: CC0 Public Domain Yale researchers have found ways to treat stroke patients that may otherwise be untreatable. In a study published in the Journal of Neurosurgery, principal investigators Yale’s Charles Matouk, MD, associate professor of neurosurgery, and Nils Petersen, MD, Ph.D. associate professor of neurology, show that a method called direct carotid puncture (DCT) […]

A conduit for prenatal inflammation?


Immune cells (in green) on the mouse choroid plexus, with blood vessels in red. Credit: Shipley et al., Neuron 2020, 10.1016/j.neuron.2020.08.024 Floating in fluid deep in the brain are small, little understood fronds of tissue. Two new studies reveal that these miniature organs are a hotbed of immune system activity. This activity may protect the […]

Hearts harvested from pigs may soon help solve chronic shortages of these donor organs


Credit: Unsplash/CC0 Public Domain The goal of harvesting hearts from pigs to solve the chronic shortage of these donor organs appears to be in reach, according to a new scientific review by researchers at Massachusetts General Hospital (MGH). This analysis, published in the journal Circulation, describes how recent breakthroughs in genetic engineering and drug development […]

Discovery holds potential for reversing vision loss


Credit: CC0 Public Domain An Oklahoma Medical Research Foundation discovery could pave the way for therapies to reverse vision loss common in premature infants and adults. In a new study appearing in the Proceedings of the National Academy of Sciences, OMRF scientists have identified a compound that could give birth to therapies for a host […]

Researchers find new way to prevent and cure rotavirus, other viral infections


Administration of IL-22 approximately doubled the rate at which rotavirus-infected cells of the intestinal wall migrated toward villus tips (second to left). Administration of IL-18 (second to right) and a combination of IL-18 and IL-22 (right) also increased the migration rate of these cells to a lesser extent. Credit: Zhang et al., Sci. Immunol. 5, […]

Childhood chemo alters heart’s caretaker cells, study finds


Gregory Aune, MD, PhD, and his team at the Greehey Children’s Cancer Research Institute, part of UT Health San Antonio, seek answers to the puzzle of why some children who receive chemotherapy go on to develop heart failure in adulthood. Credit: UT Health San Antonio Cancer chemotherapy changes the function of cells that repair heart […]

Researchers uncover clues for COVID-19 treatment


Credit: Colleen Kelley/UC Creative + Brand By examining preexisting research for other conditions, researchers at the University of Cincinnati have found a potential treatment that could be applied to COVID-19. The findings, published in the Journal of Biological Chemistry, established that a lipid found in the human body could be used to prevent or treat […]

Spontaneous Nosebleeds Tied to High Blood Pressure


High blood pressure may increase your risk for nosebleeds, a new study reports. Korean researchers studied 35,749 people, average age 52, with hypertension, and matched them to a control group of 35,749 with normal blood pressure. They tracked spontaneous nosebleeds in each group — that is, nosebleeds not caused by trauma, surgery or disease — […]

Statins reduce COVID-19 severity, likely by removing cholesterol that virus uses to infect


SARS-CoV-2 infection (green, left) is inhibited by 25HC treatment (right). Credit: UC San Diego Health Sciences There are no Food and Drug Administration (FDA)-approved treatments for COVID-19, the pandemic infection caused by a novel coronavirus. While several therapies are being tested in clinical trials, current standard of care involves providing patients with fluids and fever-reducing […]

Regenerating muscles after cancer surgery


Advancements in microsurgery are making it possible to harness the body’s healing power to regenerate muscle strength after some cancer surgeries, particularly surgery to remove soft tissue sarcoma. Mayo Clinic orthopedic oncologists are teaming with plastic surgeons in a procedure they’ve coined “oncoregeneration.” They are seeking to perfect this procedure in which large muscle is […]

Blood vessel growth in muscle is reduced in women after menopause


Credit: CC0 Public Domain A new study from the University of Copenhagen’s Department of Nutrition, Exercise and Sports demonstrates that formation of small blood vessels is impaired in the muscle tissue of postmenopausal women. The study’s findings highlight the importance of physical activity for women prior to and during menopause, as a means to prevent […]

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