Cancer-linked mutation accelerates growth of abnormal stroke-causing brain blood vessels — ScienceDaily


Researchers have discovered an explanation for why cerebral cavernous malformations (CCMs) — clusters of dilated blood vessels in the brain — can suddenly grow to cause seizures or stroke. Specifically, they found that a specific, acquired mutation in a cancer-causing gene (PIK3CA) could exacerbate existing CCMs in the brain. Furthermore, repurposing an already existing anticancer […]