Engineering T cells to attack cancer broadly — ScienceDaily


[ad_1] Through T cell engineering, researchers at Virginia Commonwealth University Massey Cancer Center show that it’s possible to arrest tumor growth for a variety of cancers and squash the spread of cancer to other tissues. This research will be published in tomorrow’s print edition of Cancer Research. The paper builds on decades of research by […]

Goethe University researchers investigate oxidative stress in mice — ScienceDaily


[ad_1] Originally, oxygen radicals — reactive oxygen species, or ROS for short — were considered to be exclusively harmful in the body. They are produced, for example, by smoking or UV radiation. Because of their high reactivity, they can damage many important molecules in cells, including the hereditary molecule DNA. As a result, there is […]

Higher mushroom consumption is associated with a lower risk of cancer — ScienceDaily


[ad_1] Next time you make a salad, you might want to consider adding mushrooms to it. That’s because higher mushroom consumption is associated with a lower risk of cancer, according to a new Penn State study, published on March 16 in Advances in Nutrition. The systematic review and meta-analysis examined 17 cancer studies published from […]

Wildfire smoke linked to skin disease — ScienceDaily


[ad_1] Wildfire smoke can trigger a host of respiratory and cardiovascular symptoms, ranging from runny nose and cough to a potentially life-threatening heart attack or stroke. A new study suggests that the dangers posed by wildfire smoke may also extend to the largest organ in the human body, and our first line of defense against […]

Findings cast doubt on industry promotion of these products as ‘safer’ alternative — ScienceDaily


[ad_1] The impact on lung cells of Heat not Burn products — a hybrid between traditional cigarettes and electronic vaping devices — may be no less harmful than that of conventional cigarettes, suggest the findings of a small comparative study, published online in the journal Thorax. Heat not burn products contain nicotine and tobacco, but […]

Dietary cocoa improves health of obese mice; likely has implications for humans — ScienceDaily


[ad_1] Supplementation of cocoa powder in the diet of high-fat-fed mice with liver disease markedly reduced the severity of their condition, according to a new study by Penn State researchers, who suggest the results have implications for people. Cocoa powder, a popular food ingredient most commonly used in the production of chocolate, is rich in […]

Scientists identify severe asthma species, show air pollutant as likely contributor — ScienceDaily


[ad_1] Asthma afflicts more than 300 million people worldwide. The most severe manifestation, known as non-Th2, or non-atopic childhood asthma, represents the majority of the cases, greater than 85%, particularly in low-income countries, according to Hyunok Choi, an associate professor at the Lehigh University College of Health. Yet, whether non-Th2 is a distinct disease (or […]

Exercise promotes healthy living and a healthy liver — ScienceDaily


[ad_1] Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder worldwide, affecting as much as a quarter of humanity. It is characterized by fat accumulation in liver cells and may progress to inflammation, cirrhosis and liver failure. Now, researchers at the University of Tsukuba reveal the positive effects, beyond the expected weight-loss benefit, […]

Gene therapy shows promise in treating rare eye disease in mice — ScienceDaily


[ad_1] A gene therapy protects eye cells in mice with a rare disorder that causes vision loss, especially when used in combination with other gene therapies, shows a study published today in eLife. The findings suggest that this therapy, whether used alone or in combination with other gene therapies that boost eye health, may offer […]

Early, late stages of degenerative diseases are distinct, study shows


[ad_1] Based on thousands of experiments over more than a decade, Rice University biochemists Michael Stern and James McNew believe degenerative diseases as varied as Alzheimer’s, Parkinson’s and muscle atrophy occur in two phases (green and red) marked by distinct alterations in the activity of the signaling pathway proteins TOR, AMPK, Foxo and JNK. In […]

Researchers mine data and connect the dots about processes driving neuroblastoma


[ad_1] Michael Dyer, Ph.D., chair of the St. Jude Department of Developmental Neurobiology Credit: St. Jude Children’s Research Hospital October 14, 2020) Researchers have used insight from a comprehensive genomic analysis of neuroblastoma to learn about the process driving one of the most common childhood solid tumors. The findings revealed possible approaches for developing precision […]

Evidence of Alzheimer’s, Parkinson’s and MND in brains of young people exposed to dirty air


[ad_1] Credit: CC0 Public Domain Researchers looking at the brainstems of children and young adults exposed lifelong to air pollution in Mexico City have discovered disturbing evidence of harm. Previous studies have linked fine particulate air pollution exposure with Alzheimer’s disease, and researchers have also reported evidence of air pollution-derived nanoparticles in the frontal cortex […]

Exercise hormone may modulate genes associated with replication of novel coronavirus


[ad_1] Brazilian researchers observed that in uninfected adipocytes, the hormone irisin altered the expression of genes that regulate ACE-2, which encodes a protein to which the virus binds in order to invade human cells. Credit: Miriane de Oliveira A study conducted by researchers at São Paulo State University (UNESP) suggests that irisin, a hormone secreted […]

Brain estrogen is key to brain protection when oxygen is low


[ad_1] Dr. Darrell Brann and Dr. Yujiao Lu from Medical College of Georgia at Augusta University. Credit: Phil Jones, Senior Photographer, Augusta University When the brain isn’t getting enough oxygen, estrogen produced by neurons in both males and females hyperactivates another brain cell type called astrocytes to step up their usual support and protect brain […]